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Why do some men experience a prolonged erection (priapism) with Cenforce 120 Mg?

Priapism, a prolonged and often painful erection lasting more than four hours, is a rare but serious side effect associated with medications like sildenafil citrate, the active ingredient in Cenforce 120 mg. Priapism occurs when blood becomes trapped in the penis, leading to persistent engorgement and potentially damaging the erectile tissue.

While priapism is uncommon with sildenafil use, it can occur due to the medication's effects on blood flow regulation. Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which regulates blood flow in the penis. In some cases, this inhibition can lead to an imbalance in the mechanisms that control penile erection and detumescence (return to the flaccid state), resulting in priapism.

Several factors may increase the risk of priapism with sildenafil use, including:

Overdose: Taking more than the recommended dose of sildenafil can increase the risk of priapism.

Underlying conditions: Certain medical conditions, such as sickle cell disease, leukemia, or multiple myeloma, may predispose individuals to priapism when using sildenafil.

Concomitant medications: Concurrent use of medications that affect blood flow or coagulation, such as anticoagulants or alpha-blockers, may increase the risk of priapism.

Personal predisposition: Some individuals may be more susceptible to priapism due to genetic or physiological factors.

It's essential for individuals taking medications like Cenforce 120mg to be aware of the signs and symptoms of priapism, including persistent erection unrelated to sexual stimulation, penile pain, and tenderness. If priapism occurs, immediate medical attention is necessary to prevent complications such as tissue damage and permanent erectile dysfunction.

To minimize the risk of priapism, individuals should use sildenafil as prescribed by a healthcare provider and avoid exceeding the recommended dosage. Additionally, any concerns or questions about medication use should be discussed with a healthcare provider to ensure safe and appropriate use.