Extra Super Vidalista is a medication primarily used to treat erectile dysfunction (ED) and premature ejaculation (PE). It contains two active ingredients: Tadalafil, which is a phosphodiesterase type 5 (PDE5) inhibitor, and Dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI).

When it comes to antifungal medications, particularly azole antifungals like fluconazole, it's important to note that they can inhibit the metabolism of certain drugs by inhibiting cytochrome P450 enzymes, particularly CYP3A4. Tadalafil, one of the active ingredients in Extra Super Vidalista, is metabolized primarily by CYP3A4. Therefore, concurrent use of antifungal medications like fluconazole could potentially increase the blood levels of tadalafil, leading to an increased risk of tadalafil-related adverse effects such as headache, flushing, dizziness, or low blood pressure.

Conversely, Dapoxetine, the other active ingredient in Extra Super Vidalista, is primarily metabolized by CYP2D6 and CYP3A4. While azole antifungals can inhibit CYP3A4, they may not have a significant impact on CYP2D6 metabolism. However, caution should still be exercised when combining antifungal medications with Extra Super Vidalista to monitor for any potential adverse effects.

As always, it's crucial to consult with a healthcare provider before combining medications, as they can provide personalized advice based on your medical history and specific circumstances.