William Shatner irritated me the most. In both episodes, "Butterfly in Shades of Grey" and "Fade into Murder." He is so arrogant and self-centered, I don't even watch those episodes.
Just thought of another total creep. Dr. Collier. Murdering the very mentally ill Nadia Donner was very bad. Especially the way he did it.
Jarvis Goodland in the Greenhouse Jungle! His whole attitude to everyone, his nephew, his wife, Columbo!