In Requiem For A Falling Star, Columbo tries to call his wife from Nora Chandler's bungalow but he only gets to talk to his brother-in-law George because Mrs. Columbo went shopping again. Columbo asks George if he knows where he's at and then says, "Don't get smart, George." What do you suppose George's reply to Columbo was? I've always thought that he replied, "Jail?"

Maybe he said, "I think she ran off with the pool boy from next door again".

I misread your question as "Where's she at?" vs. "Do you know where I am?"

I'll give another answer that could result in the "Don't get smart with me, George" reply.

"The strip joint again?"