I'll have to admit, for many years I didn't even realize that Harry had actually died, since (if I remember correctly) there isn't any explicit mention of it. Of course, it's implicit in the context of the story that he died, which just struck me fairly recently. Also, if I'm not mistaken, with Harry being murdered, that makes Dr. Mayfield the only triple murderer (well, one is an attempted murder) in the series. Of course, Ruth Lytton in "Old Fashioned Murder" had three victims, but only two were a part of the present story.
And I agree with you, J, the scene where Columbo shakes up Mayfield is extremely effective. I like how you worded it, too, with Columbo USING anger against Mayfield. When he loses his temper with Milo Janus in "Exercise in Fatality" (which is a great scene, too) it seems less that he's using anger as a tactic, and more that he's genuinely indignant toward Milo. He supposedly used anger against Joan Hudson in "Prescription Murder", too, but that scene for me just comes off as disturbing and out-of-character, unlike the scene with Mayfield.

J, There are three more episodes I have seen Columbo display anger: "An Exercise In Fatality", "Mind Over Mayhem", and "Murder Under Glass". I will not spoil it by pointing them out unless you want me to.

Another is DEADY STATE OF MIND. I've never been fond of that line directed at Dr. Borden - "No, I'm asking YOU!"
All right, it isn't actually SHOUTED at her, but it is unpleasant. It's a little like the big moment between Columbo and Joan Hudson, but even less called for, since this person isn't some accomplice.

Grant, I meant the episode you mentioned instead of "Mind Over Mayhem". Sorry

That's understandable. I confuse those two titles constantly.