Hi Kim,
I have been on sertraline for 5 months now. It takes a while for the tablets to work. You do not notice a huge difference over night, just things improving slowly until one day you see hints of the "old you" re-surfacing.
I also suffered from depersonalisation and only get it every now and again on my bad days which thankfully are getting few and further between.
It's tough starting off but you are two weeks done so well done!